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Research Group Nave

Cardiometabolic risk factors and stroke

Personalized rehabilitation after stroke

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PD Alexander H. Nave, MD

Interdiscplinary Stroke Research

CCM: Campus Charité Mitte

Portrait of Alexander H. Nave, MD

Site under construction.

Selected publications

The Dynamic of Extracellular Vesicles in Patients With Subacute Stroke: Results of the "Biomarkers and Perfusion-Training-Induced Changes After Stroke" (BAPTISe) Study.
Jödicke RA, Huo S, Kränkel N, Piper SK, Ebinger M, Landmesser U, Flöel A, Endres M, Nave AH.
Front Neurol. 2021 Nov 8;12:731013. doi: 10.3389/fneur.2021.731013. eCollection 2021.
PMID: 34819906 Free PMC article.

Evolution of Blood-Brain Barrier Permeability in Subacute Ischemic Stroke and Associations With Serum Biomarkers and Functional Outcome.
Müller S, Kufner A, Dell'Orco A, Rackoll T, Mekle R, Piper SK, Fiebach JB, Villringer K, Flöel A, Endres M, Ebinger M, Nave AH. Front Neurol. 2021 Oct 20;12:730923. doi: 10.3389/fneur.2021.730923. eCollection 2021.
PMID: 34744972 Free PMC article.

Elevated Serum Inflammatory Markers in Subacute Stroke Are Associated With Clinical Outcome but Not Modified by Aerobic Fitness Training: Results of the Randomized Controlled PHYS-STROKE Trial.
Kirzinger B, Stroux A, Rackoll T, Endres M, Flöel A, Ebinger M, Nave AH. Front Neurol. 2021 Aug 26;12:713018. doi: 10.3389/fneur.2021.713018. eCollection 2021.
PMID: 34512526 Free PMC article. Clinical Trial.

Magnetic resonance imaging-based changes in vascular morphology and cerebral perfusion in subacute ischemic stroke.
Kufner A, Khalil AA, Galinovic I, Kellner E, Mekle R, Rackoll T, Boehm-Sturm P, Fiebach JB, Flöel A, Ebinger M, Endres M, Nave AH. J Cereb Blood Flow Metab. 2021 Oct;41(10):2617-2627. doi: 10.1177/0271678X211010071. Epub 2021 Apr 17.
PMID: 33866849 Free PMC article. Clinical Trial.

Physical Fitness Training in Patients with Subacute Stroke (PHYS-STROKE): Safety analyses of a randomized clinical trial.
Rackoll T, Nave AH, Ebinger M, Endres M, Grittner U, Flöel A; ; for the PHYS-Stroke study group. Int J Stroke. 2021 Apr 7:17474930211006286. doi: 10.1177/17474930211006286. Online ahead of print.
PMID: 33724085 Free article.

Endothelial and Leukocyte-Derived Microvesicles and Cardiovascular Risk After Stroke: PROSCIS-B.
Huo S, Kränkel N, Nave AH, Sperber PS, Rohmann JL, Piper SK, Heuschmann PU, Landmesser U, Endres M, Siegerink B, Liman TG. Neurology. 2021 Feb 9;96(6):e937-e946. doi: 10.1212/WNL.0000000000011223. Epub 2020 Nov 12.
PMID: 33184230

Physical Fitness Training in Patients with Subacute Stroke (PHYS-STROKE): multicentre, randomised controlled, endpoint blinded trial.
Nave AH, Rackoll T, Grittner U, Bläsing H, Gorsler A, Nabavi DG, Audebert HJ, Klostermann F, Müller-Werdan U, Steinhagen-Thiessen E, Meisel A, Endres M, Hesse S, Ebinger M, Flöel A. BMJ. 2019 Sep 18;366:l5101. doi: 10.1136/bmj.l5101.
PMID: 31533934 Free PMC article. Clinical Trial.

Hyperintense Vessels, Collateralization, and Functional Outcome in Patients With Stroke Receiving Endovascular Treatment.
Nave AH, Kufner A, Bücke P, Siebert E, Kliesch S, Grittner U, Bäzner H, Liebig T, Endres M, Fiebach JB, Nolte CH, Ebinger M, Henkes H. Stroke. 2018 Mar;49(3):675-681. doi: 10.1161/STROKEAHA.117.019588. Epub 2018 Feb 19.
PMID: 29459394 Clinical Trial.

Lipoprotein(a) Levels and Recurrent Vascular Events After First Ischemic Stroke.
Lange KS, Nave AH, Liman TG, Grittner U, Endres M, Ebinger M. Stroke. 2017 Jan;48(1):36-42. doi: 10.1161/STROKEAHA.116.014436. Epub 2016 Nov 17.
PMID: 27856951 Clinical Trial.

Lipoprotein (a) as a risk factor for ischemic stroke: a meta-analysis.
Nave AH, Lange KS, Leonards CO, Siegerink B, Doehner W, Landmesser U, Steinhagen-Thiessen E, Endres M, Ebinger M. Atherosclerosis. 2015 Oct;242(2):496-503. doi: 10.1016/j.atherosclerosis.2015.08.021. Epub 2015 Aug 15.
PMID: 26298741


  • Torsten Rackoll
  • Nurcennet Kaynak
  • Charlotte Pietrock
  • Valentin Kennel
  • Gloria Greta Gelfert

Former team members

  • Ruben Jödicke
  • Bernadette Kirzinger
  • Sarah Müller